×
Entrez Id: 3782
Gene Symbol: KCNN3
KCNN3
0.310
Biomarker
disease
GENOMICS_ENGLAND
A de novo mutation in KCNN3 associated with autosomal dominant idiopathic non-cirrhotic portal hypertension.
26658685 2016
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.540
Biomarker
disease
RGD
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
26627607 2016
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.510
Biomarker
disease
RGD
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.
16142243 2005
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.510
Therapeutic
disease
RGD
Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats.
29263339 2017
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.510
Biomarker
disease
RGD
Role of aortic nitric oxide synthase 3 (eNOS) in the systemic vasodilation of portal hypertension.
10889169 2000
×
Entrez Id: 551
Gene Symbol: AVP
AVP
0.500
Biomarker
disease
RGD
Restriction of drinking water abrogates splanchnic vasodilation and portal hypertension in portal vein-ligated rats.
18987488 2009
×
Entrez Id: 2153
Gene Symbol: F5
F5
0.300
Biomarker
disease
RGD
Portal hypertension and ascites in acute hepatitis: clinical, hemodynamic and histological correlations.
2777210 1989
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.230
Therapeutic
disease
RGD
Tumor necrosis factor alpha: a major contributor to the hyperdynamic circulation in prehepatic portal-hypertensive rats.
7875478 1995
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.230
Therapeutic
disease
RGD
Factors mediating the hemodynamic effects of tumor necrosis factor-alpha in portal hypertensive rats.
10070045 1999
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.230
Biomarker
disease
RGD
Hyperdynamic circulation in prehepatic portal hypertension: role of tumor necrosis factor-alpha.
9198288 1997
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.230
Biomarker
disease
RGD
Tumor necrosis factor-alpha regulates inducible nitric oxide synthase gene expression in the portal hypertensive gastric mucosa of the rat.
9834372 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.230
Therapeutic
disease
RGD
Tumor necrosis factor alpha regulates nitric oxide synthase expression in portal hypertensive gastric mucosa of rats.
9537427 1998
×
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
0.230
Biomarker
disease
RGD
Antioxidant role of heme oxygenase-1 in prehepatic portal hypertensive rats.
16830363 2006
×
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
0.220
Therapeutic
disease
RGD
Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation.
19418582 2009
×
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
0.210
Biomarker
disease
RGD
Activation of eNOS in rat portal hypertensive gastric mucosa is mediated by TNF-alpha via the PI 3-kinase-Akt signaling pathway.
11826414 2002
×
Entrez Id: 64506
Gene Symbol: CPEB1
CPEB1
0.210
Biomarker
disease
RGD
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
26627607 2016
×
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
0.210
Biomarker
disease
RGD
Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension.
19070926 2009
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
0.210
Therapeutic
disease
RGD
Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension.
10727442 2000
×
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.210
Biomarker
disease
RGD
[Effect and mechanism of salvianolic acid B in attenuating elevated portal pressure in a rat model of portal hypertension induced by endothelin-1].
17214938 2007
×
Entrez Id: 22846
Gene Symbol: VASH1
VASH1
0.210
ModifyingMutation
disease
RGD
Disruption of negative feedback loop between vasohibin-1 and vascular endothelial growth factor decreases portal pressure, angiogenesis, and fibrosis in cirrhotic rats.
24390792 2014
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.200
Biomarker
disease
RGD
Tumor necrosis factor-alpha, interleukin-1beta and nitric oxide: induction of liver megamitochondria in prehepatic portal hypertensive rats.
15951934 2005
×
Entrez Id: 5617
Gene Symbol: PRL
PRL
0.200
Biomarker
disease
RGD
Role of ammonia and nitric oxide in the decrease in plasma prolactin levels in prehepatic portal hypertensive male rats.
17119344 2006
×
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
0.200
Biomarker
disease
RGD
[Effect and mechanism of salvianolic acid B in attenuating elevated portal pressure in a rat model of portal hypertension induced by endothelin-1].
17214938 2007
×
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
0.200
Biomarker
disease
RGD
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats.
17351970 2007
×
Entrez Id: 7054
Gene Symbol: TH
TH
0.200
Biomarker
disease
RGD
Atrophy of mesenteric sympathetic innervation may contribute to splanchnic vasodilation in rat portal hypertension.
19968782 2010